Preclinical pharmacology and pharmacokinetics of CERC‐301, a GluN2B‐selective N ‐methyl‐D‐aspartate receptor antagonist
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منابع مشابه
Preclinical pharmacology and pharmacokinetics of CERC‐301, a GluN2B‐selective N‐methyl‐D‐aspartate receptor antagonist
The preclinical pharmacodynamic and pharmacokinetic properties of 4-methylbenzyl (3S, 4R)-3-fluoro-4-[(Pyrimidin-2-ylamino) methyl] piperidine-1-carboxylate (CERC-301), an orally bioavailable selective N-methyl-D-aspartate (NMDA) receptor subunit 2B (GluN2B) antagonist, were characterized to develop a translational approach based on receptor occupancy (RO) to guide CERC-301 dose selection in cl...
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ژورنال
عنوان ژورنال: Pharmacology Research & Perspectives
سال: 2015
ISSN: 2052-1707,2052-1707
DOI: 10.1002/prp2.198